Publications

Journal Publications & Patents (2021–2026)

2026

  • Methods and systems for accessing anatomical spaces
    M Singh, JU Kang
    US Patent App. 19/400,713
  • Real-time topology-aware M-mode OCT segmentation method for robotic deep interior lamellar keratoplasty (DALK) surgical guidance
    R Xiong, J Yu, Y Wang, Z Huang, JU Kang
    Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems
  • Binary pattern-based single-shot fringe projection profilometry for real-time laparoscopic surgical guidance
    WW Rodgers, R Zuo, J Yu, S Jang, S Wei, J Opfermann, A Krieger, …
    Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems
  • Real-time topology-aware M-mode OCT segmentation for robotic deep anterior lamellar keratoplasty (DALK) guidance
    R Xiong, J Yu, Y Wang, Z Huang, JU Kang
    arXiv preprint arXiv:2602.02798
  • End-to-end reconstruction of OCT optical properties and speckle-reduced structural intensity via physics-based learning
    J Yu, Y Wang, W Guo, Y Gao, Y Sun, JU Kang
    arXiv preprint arXiv:2602.02721
  • Wide-field high-resolution microscopy via high-speed galvo scanning and real-time mosaicking
    Z Huang, R Xiong, Y Wang, J Yu, JU Kang
    arXiv preprint arXiv:2602.02758
  • Super-Resolution and Denoising of Corneal B-Scan OCT Imaging Using Diffusion Model Plug-and-Play Priors
    Y Wang, J Yu, W Guo, Z Huang, R Xiong, Y Sun, JU Kang
    arXiv preprint arXiv:2602.02795
  • Physics-based generation of multilayer corneal OCT data via Gaussian modeling and MCML for AI-driven diagnostic and surgical guidance applications
    J Yu, Y Wang, R Xiong, Z Huang, K Irsch, JU Kang
    arXiv preprint arXiv:2602.02755

2025

  • Psi3d: Plug-and-play 3d stochastic inference with slice-wise latent diffusion prior
    W Guo, J Yu, Y Wang, JU Kang, Y Sun
    arXiv preprint arXiv:2512.18367
  • Compact endoscope design for three-dimensional surgical guidance
    JU Kang, HND Le
    US Patent App. 19/015,310
  • Deep-learning-based endoscopic single-shot fringe projection profilometry
    R Zuo, S Wei, Y Wang, R Huang, WW Rodgers, J Yu, MH Hsieh, A Krieger, …
    Journal of Biomedical Optics 30 (8), 086003-086003
  • Neuromodulation based nerve identification
    EM Boctor, J Kang, AL Burnett, JU Kang, M HARRAZ
    US Patent App. 19/174,285
  • Super-resolution optical coherence tomography using diffusion model-based plug-and-play priors
    Y Wang, J Yu, W Guo, Y Sun, JU Kang
    arXiv preprint arXiv:2505.14916
  • Neuromodulation based nerve identification
    EM Boctor, J Kang, AL Burnett, JU Kang, M HARRAZ
    US Patent 12,274,530
  • Kalman filter/deep-learning hybrid automatic boundary tracking of optical coherence tomography data for deep anterior lamellar keratoplasty (DALK)
    H Yi, J Yu, Y Wang, J Opfermann, BG Gensheimer, A Kriger, JU Kang
    Optical Fibers and Sensors for Medical Diagnostics, Treatment, and…
  • Topology-based deep-learning segmentation method for deep anterior lamellar keratoplasty (DALK) surgical guidance using M-mode OCT data
    J Yu, H Yi, Y Wang, JD Opfermann, WG Gensheimer, A Krieger, JU Kang
    Optical Fibers and Sensors for Medical Diagnostics, Treatment, and…
  • Development of an image-guided non-vitrectomy subretinal access approach for trans-scleral cell and gene therapy delivery
    MS Singh, S Guo, CB Toomey, M McNally, S Harris-Bookman, K Li, …
    bioRxiv, 2025.02. 25.640217

2024

  • Reimagining partial thickness keratoplasty: An eye mountable robot for autonomous big bubble needle insertion
    Y Wang, JD Opfermann, J Yu, H Yi, J Kaluna, R Biswas, R Zuo, …
    arXiv preprint arXiv:2410.14577
  • Autonomous robotic system with optical coherence tomography guidance for vascular anastomosis
    J Haworth, R Biswas, J Opfermann, M Kam, Y Wang, D Pantalone, …
    arXiv preprint arXiv:2410.07493
  • The use of ectopic volar fibroblasts to modify skin identity
    SS Lee, E Sweren, E Dare, P Derr, K Derr, CC Wang, B Hardesty, …
    Science 385 (6713), eadi1650
  • High-resolution in vivo 4D-OCT fish-eye imaging using 3D-UNet with multi-level residue decoder
    R Zuo, S Wei, Y Wang, K Irsch, JU Kang
    Biomedical Optics Express 15 (9), 5533-5546
  • A robotic injection system for consistent pneumo-dissection of the deep stroma in big bubble DALK surgery
    J Kaluna, JD Opfermann, Y Wang, JU Kang, W Gensheimer, A Krieger
    46th Annual International Conference of the IEEE Engineering in…
  • Live porcine eye model studies of subretinal injection using handheld endoscopy OCT integrated injector
    MS Singh, K Li, J Yu, X Liu, JU Kang
    Investigative Ophthalmology & Visual Science 65 (7), 5499-5499
  • Comparison of vertical cannula insertion techniques for big bubble deep anterior lamellar keratoplasty
    WG Gensheimer, J Opfermann, Y Wang, J Kaluna, A Krieger, JU Kang
    Investigative Ophthalmology & Visual Science 65 (7), 3700-3700
  • Novel vertical big bubble needle approach vs. the standard approach for deep anterior lamellar keratoplasty (DALK)
    J Opfermann, Y Wang, J Kaluna, A Krieger, JU Kang, WG Gensheimer
    Investigative Ophthalmology & Visual Science 65 (7), 3684-3684
  • Design and evaluation of an eye mountable AutoDALK robot for deep anterior lamellar keratoplasty
    JD Opfermann, Y Wang, J Kaluna, K Suzuki, W Gensheimer, A Krieger, …
    Micromachines 15 (6), 788
  • Multicore fiber optic imaging reveals that astrocyte calcium activity in the mouse cerebral cortex is modulated by internal motivational state
    YTA Gau, ET Hsu, RJ Cha, RW Pak, LL Looger, JU Kang, DE Bergles
    Nature Communications 15 (1), 3039
  • High resolution in vivo 4D-OCT fish eye imaging using deep learning
    R Zuo, S Wei, Y Wang, K Irsch, JU Kang
    Optical Coherence Tomography, CTu3E. 4
  • Automatic and real-time tissue sensing for autonomous intestinal anastomosis using hybrid MLP-DC-CNN classifier-based optical coherence tomography
    Y Wang, S Wei, R Zuo, M Kam, JD Opfermann, I Sunmola, MH Hsieh, …
    Biomedical Optics Express 15 (4), 2543-2560
  • Live rabbit eye model studies of optical coherence tomography guided pneumatic dissection using vertically inserted razor edge cannula for deep anterior lamellar keratoplasty
    Y Wang, JD Opfermann, J Kaluna, R Zuo, J Haworth, A Krieger, …
    Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems…
  • Deep learning-based single-shot fringe projection profilometry
    R Zuo, S Wei, Y Wang, M Kam, JD Opfermann, MH Hsieh, A Krieger, …
    Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems…
  • Towards autonomous retinal microsurgery using RGB-D images
    JW Kim, S Wei, P Zhang, P Gehlbach, JU Kang, I Iordachita, M Kobilarov
    IEEE Robotics and Automation Letters 9 (4), 3807-3814
  • Arc-to-line frame registration method for ultrasound and photoacoustic image-guided intraoperative robot-assisted laparoscopic prostatectomy
    H Song, S Yang, Z Wu, H Moradi, RH Taylor, JU Kang, SE Salcudean, …
    International Journal of Computer Assisted Radiology and Surgery 19 (2), 199-208
  • Photoacoustic imaging with photoacoustic markers: an ex vivo demonstration
    H Song, H Moradi, B Jiang, Y Wu, R Taylor, A Deguet, JU Kang, …
    Authorea Preprints

2023

  • Development and Evaluation of a Single-arm Robotic System for Autonomous Suturing
    J Liu, M Kam, JD Opfermann, Z Zhang, MH Hsieh, JU Kang, A Krieger
    2023 IEEE/RSJ International Conference on Intelligent Robots and Systems…
  • Depth-dependent attenuation and backscattering characterization of optical coherence tomography by stationary iterative method
    Y Wang, S Wei, JU Kang
    Journal of Biomedical Optics 28 (8), 085002-085002
  • Towards Deep Learning Guided Autonomous Eye Surgery Using Microscope and iOCT Images
    JW Kim, S Wei, P Zhang, P Gehlbach, JU Kang, I Iordachita, M Kobilarov
    arXiv preprint arXiv:2306.10127
  • Needle Insertion Force Profile of Rabbit Corneas with Relevance to Deep Anterior Lamellar Keratoplasty (DALK)
    WG Gensheimer, J Kaluna, J Opfermann, Y Wang, A Krieger, J Kang
    Investigative Ophthalmology & Visual Science 64 (8), 4808-4808
  • Development and Evaluation of a Robotic Vessel Positioning System for Semi-Automatic Microvascular Anastomosis
    J Haworth, J Opfermann, M Kam, Y Wang, R Yang, JU Kang, A Krieger
    2023 IEEE International Conference on Robotics and Automation (ICRA), 6901-6908
  • Multicore fiber optic imaging reveals that astrocyte calcium activity in the cerebral cortex is modulated by internal motivational state
    YTA Gau, E Hsu, J Cha, RW Pak, LL Looger, JU Kang, DE Bergles
    bioRxiv
  • Autonomous system for vaginal cuff closure via model-based planning and markerless tracking techniques
    M Kam, S Wei, JD Opfermann, H Saeidi, MH Hsieh, KC Wang, JU Kang, …
    IEEE Robotics and Automation Letters 8 (7), 3916-3923
  • Implementation of cost-effective common path spectral domain free-hand Scanning OCT system
    S Guo, X Liu, JU Kang
    Current Optics and Photonics 7 (2), 176-182
  • Optical image-guided autonomous robotic surgery
    JU Kang
    Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems…
  • Demonstration of in vivo real-time 3D motion-compensated OCT volumetric imaging using a CNN-based algorithm
    R Zuo, K Irsch, JU Kang
    Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems…
  • Common-path optical coherence tomography guided vertical pneumodissection for DALK
    Y Wang, S Guo, JD Opfermann, J Kaluna, BG Gensheimer, A Krieger, …
    Optical Fibers and Sensors for Medical Diagnostics, Treatment and…
  • OCT-guided robotic subretinal needle injections: A deep learning-based registration approach
    K Mach, S Wei, JW Kim, A Martin-Gomez, P Zhang, JU Kang, MA Nasseri, …
    2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM…

2022

  • Unsupervised and quantitative intestinal ischemia detection using conditional adversarial network in multimodal optical imaging
    Y Wang, L Tiusaba, S Jacobs, M Saruwatari, B Ning, M Levitt, AD Sandler, …
    Journal of Medical Imaging 9 (6), 064502-064502
  • Real-time intraoperative surgical guidance system in the da Vinci surgical robot based on transrectal ultrasound/photoacoustic imaging with photoacoustic markers: an ex vivo…
    H Song, H Moradi, B Jiang, K Xu, Y Wu, RH Taylor, A Deguet, JU Kang, …
    IEEE Robotics and Automation Letters 8 (3), 1287-1294
  • Convolutional neural network-based common-path optical coherence tomography A-scan boundary-tracking training and validation using a parallel Monte Carlo synthetic dataset
    S Guo, JU Kang
    Optics Express 30 (14), 25876-25890
  • Higher-order regression three-dimensional motion-compensation method for real-time optical coherence tomography volumetric imaging of the cornea
    R Zuo, K Irsch, JU Kang
    Journal of Biomedical Optics 27 (6), 066006-066006
  • Overcoming the Force Limitations of Magnetic Robotic Surgery: Magnetic Pulse Actuated Collisions for Tissue‐Penetrating‐Needle for Tetherless Interventions
    O Erin, X Liu, J Ge, J Opfermann, Y Barnoy, LO Mair, JU Kang, …
    Advanced Intelligent Systems 4 (6), 2200072
  • External and internal intraoperative optical coherence tomography imaging for subretinal material delivery
    JU Kang, M Singh
    US Patent App. 17/428,848
  • Region targeted robotic needle guidance using a camera-integrated optical coherence tomography
    S Wei, JW Kim, A Martin-Gomez, P Zhang, I Iordachita, JU Kang
    Optical Coherence Tomography, CM2E. 6
  • Deep point cloud landmark localization for fringe projection profilometry
    S Wei, M Kam, Y Wang, JD Opfermann, H Saeidi, MH Hsieh, A Krieger, …
    Journal of the Optical Society of America A 39 (4), 655-661
  • Numerical landmark detection algorithm for fringe projection profilometry during autonomous robotic suturing
    S Wei, M Kam, Y Wang, JD Opfermann, H Saeidi, MH Hsieh, A Krieger, …
    Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX…
  • 3D motion-compensated optical coherence tomography based on higher-order regression towards real-time volumetric imaging of the cornea
    R Zuo, Y Wang, K Irsch, JU Kang
    Optical Coherence Tomography and Coherence Domain Optical Methods in…
  • Assessment of temporal changes in thickness and needle insertion force in rabbit corneas during storage
    S Guo, J Opfermann, WG Gensheimer, A Krieger, JU Kang
    Ophthalmic Technologies XXXII, PC119411A
  • Depth-resolved backscattering signal reconstruction based OCT attenuation compensation
    Y Wang, S Wei, JU Kang
    Proceedings of SPIE–the International Society for Optical Engineering 11953…
  • Automated OCT A-line abdominal tissue classification using a hybrid MLP-CNN classifier during ventral hernia repair
    Y Wang, S Wei, JD Opfermann, M Kam, H Saeidi, MH Hsieh, A Krieger, …
    Optical Fibers and Sensors for Medical Diagnostics, Treatment and…
  • Downward viewing common-path optical coherence tomography guided hydro-dissection needle for DALK
    S Guo, J Opfermann, WG Gensheimer, A Krieger, JU Kang
    Optical Fibers and Sensors for Medical Diagnostics, Treatment and…
  • Autonomous robotic laparoscopic surgery for intestinal anastomosis
    H Saeidi, JD Opfermann, M Kam, S Wei, S Léonard, MH Hsieh, JU Kang, …
    Science Robotics 7 (62), eabj2908
  • Autonomous robotic laparoscopic surgery for intestinal anastomosis. Sci Robot 7: eabj2908
    H Saeidi, JD Opfermann, M Kam, S Wei, S Leonard, MH Hsieh, JU Kang, …
  • Transcranial photoacoustic imaging of NMDA-evoked focal circuit dynamics in rat hippocampus
    DF Wong, A Gjedde, SD Kadam, JS Elmore, BJ Sullivan, H Valentine, …
    Journal of Cerebral Blood Flow and Metabolism 41 (1_ SUPPL), 74-75

2021

  • Optimization of near-infrared fluorescence voltage-sensitive dye imaging for neuronal activity monitoring in the rodent brain
    RW Pak, J Kang, E Boctor, JU Kang
    Frontiers in Neuroscience 15, 742405
  • Retinal implantation device
    M Singh, K WOLFE, JU Kang, K Perrino, AC Timm
    US Patent App. 17/265,668
  • A novel wax based piezo actuator for autonomous deep anterior lamellar keratoplasty (piezo-dalk)
    JD Opfermann, M Barbic, M Khrenov, S Guo, NR Sarfaraz, JU Kang, …
    2021 IEEE/RSJ International Conference on Intelligent Robots and Systems…
  • Breaking barriers in robotic soft tissue surgery: Conditional autonomous intestinal anastomosis
    H Saeidi, JD Opfermann, M Kam, S Wei, S Léonard, MH Hsieh, JU Kang, …
    arXiv preprint arXiv:2107.01288
  • Stabilizing the phase of swept-source optical coherence tomography by a wrapped Gaussian mixture model
    S Wei, JU Kang
    Optics Letters 46 (12), 2932-2935
  • CNN-based CP-OCT sensor integrated with a subretinal injector for retinal boundary tracking and injection guidance
    S Lee, JU Kang
    Journal of Biomedical Optics 26 (6), 068001-068001
  • A confidence-based supervised-autonomous control strategy for robotic vaginal cuff closure
    M Kam, H Saeidi, MH Hsieh, JU Kang, A Krieger
    2021 IEEE international conference on robotics and automation (ICRA), 12261…
  • Convolutional neural network-based optical coherence tomography (OCT) A-scan segmentation and tracking platform using advanced monte Carlo simulation
    S Guo, JU Kang
    Optical Molecular Probes, Imaging and Drug Delivery, JW1A. 16
  • Optimized OCT-based depth-resolved model for attenuation compensation using point-spread-function calibration
    Y Wang, S Wei, S Guo, JU Kang
    Optical Fibers and Sensors for Medical Diagnostics, Treatment and…
  • Optical flow optical coherence tomography for determining accurate velocity fields
    S Wei, JU Kang
    Optical Coherence Tomography and Coherence Domain Optical Methods in…
  • Fluorescence dual-color fiberscope for monitoring neuron and astrocyte concurrent activities in freely-behaving animals
    RW Pak, E Hsu, G Molina-Castro, DE Bergles, JU Kang
    Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics 11629…
  • Motion-compensated optical coherence tomography based on higher-order regression for real-time volumetric imaging
    R Zuo, K Irsch, JU Kang
    Optical Coherence Tomography and Coherence Domain Optical Methods in…
  • Small infrared target detection based on fast adaptive masking and scaling with iterative segmentation
    Y Chen, G Zhang, Y Ma, JU Kang, C Kwan
    IEEE Geoscience and Remote Sensing Letters 19, 1-5
  • Deep learning-guided autonomous retinal surgery using a robotic arm, microscopy, and iOCT imaging
    JW Kim, S Wei, P Zhang, P Gehlbach, JU Kang, I Iordachita, M Kobilarov
    J LaTeX Class Files 14 (8)
  • Molecular radiative energy shifts under strong oscillating fields
    P Zheng, J Kang, D Paria, JU Kang, I Barman
    Small 17 (3), 2007244

Book Publication

J. U. Kang ed. Fiber Optic Sensing and Imaging. New York, NY: Springer 2013.41XXj6yOpsL._BO2,204,203,200_PIsitb-sticker-arrow-click,TopRight,35,-76_AA300_SH20_OU01_